高橋 美樹子
薬学部 薬学科 | 教授 |
Last Updated :2025/06/19
■研究者基本情報
■経歴
経歴
■研究活動情報
論文
- LRBA is essential for urinary concentration and body water homeostasis.
Yu Hara; Fumiaki Ando; Daisuke Oikawa; Koichiro Ichimura; Hideki Yanagawa; Yuriko Sakamaki; Azuma Nanamatsu; Tamami Fujiki; Shuichi Mori; Soichiro Suzuki; Naofumi Yui; Shintaro Mandai; Koichiro Susa; Takayasu Mori; Eisei Sohara; Tatemitsu Rai; Mikiko Takahashi; Sei Sasaki; Hiroyuki Kagechika; Fuminori Tokunaga; Shinichi Uchida
Proceedings of the National Academy of Sciences of the United States of America, 2022年07月26日, [査読有り] - The Cep57-pericentrin module organizes PCM expansion and centriole engagement.
Koki Watanabe; Daisuke Takao; Kei K Ito; Mikiko Takahashi; Daiju Kitagawa
Nature communications, 2019年02月25日, [査読有り] - Mutant analysis of Cdt1's function in suppressing nascent strand elongation during DNA replication in Xenopus egg extracts.
Yuta Nakazaki; Takashi Tsuyama; Yutaro Azuma; Mikiko Takahashi; Shusuke Tada
Biochemical and biophysical research communications, 2017年09月02日, [査読有り] - CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells.
Jing Wang; Honglin Xu; Yuqiang Jiang; Mikiko Takahashi; Masatoshi Takeichi; Wenxiang Meng
Journal of genetics and genomics = Yi chuan xue bao, 2017年01月20日, [査読有り] - Excess Cdt1 inhibits nascent strand elongation by repressing the progression of replication forks in Xenopus egg extracts.
Yuta Nakazaki; Takashi Tsuyama; Masayuki Seki; Mikiko Takahashi; Takemi Enomoto; Shusuke Tada
Biochemical and biophysical research communications, 2016年02月05日, [査読有り] - MTCL1 crosslinks and stabilizes non-centrosomal microtubules on the Golgi membrane.
Yoshinori Sato; Kenji Hayashi; Yoshiko Amano; Mikiko Takahashi; Shigenobu Yonemura; Ikuko Hayashi; Hiroko Hirose; Shigeo Ohno; Atsushi Suzuki
Nature communications, 2014年11月04日, [査読有り] - More isn't always better: limiting centrosome size in interphase.
Mikiko Takahashi; Kazuhiko Matsuo
Cell cycle (Georgetown, Tex.), 2013年05月15日
責任著者 - Kendrin is a novel substrate for separase involved in the licensing of centriole duplication.
Kazuhiko Matsuo; Keita Ohsumi; Mari Iwabuchi; Toshio Kawamata; Yoshitaka Ono; Mikiko Takahashi
Current biology : CB, 2012年05月22日, [査読有り]
ラスト(シニア)オーサー, 責任著者 - AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier properties.
Seema Sehrawat; Thomas Ernandez; Xavier Cullere; Mikiko Takahashi; Yoshitaka Ono; Yulia Komarova; Tanya N Mayadas
Blood, 2011年01月13日, [査読有り] - Involvement of a centrosomal protein kendrin in the maintenance of centrosome cohesion by modulating Nek2A kinase activity.
Kazuhiko Matsuo; Tamako Nishimura; Akihide Hayakawa; Yoshitaka Ono; Mikiko Takahashi
Biochemical and biophysical research communications, 2010年07月23日, [査読有り]
ラスト(シニア)オーサー - Accumulation of tumor-suppressor PTEN in Alzheimer neurofibrillary tangles.
Yuma Sonoda; Hideyuki Mukai; Kazuhiko Matsuo; Mikiko Takahashi; Yoshitaka Ono; Kiyoshi Maeda; Haruhiko Akiyama; Toshio Kawamata
Neuroscience letters, 2010年02月26日, [査読有り] - A peptidyl-prolyl isomerase, FKBP12, accumulates in Alzheimer neurofibrillary tangles.
Hisato Sugata; Kazuhiko Matsuo; Taisuke Nakagawa; Mikiko Takahashi; Hideyuki Mukai; Yoshitaka Ono; Kiyoshi Maeda; Haruhiko Akiyama; Toshio Kawamata
Neuroscience letters, 2009年08月07日, [査読有り] - AMP-activated protein kinase phosphorylates Golgi-specific brefeldin A resistance factor 1 at Thr1337 to induce disassembly of Golgi apparatus.
Takafumi Miyamoto; Noriko Oshiro; Ken-ichi Yoshino; Akio Nakashima; Satoshi Eguchi; Mikiko Takahashi; Yoshitaka Ono; Ushio Kikkawa; Kazuyoshi Yonezawa
The Journal of biological chemistry, 2008年02月15日, [査読有り] - Recruitment of CG-NAP to the Golgi apparatus through interaction with dynein-dynactin complex.
Hon-Song Kim; Mikiko Takahashi; Kazuhiko Matsuo; Yoshitaka Ono
Genes to cells : devoted to molecular & cellular mechanisms, 2007年03月, [査読有り] - Centrosome-targeting region of CG-NAP causes centrosome amplification by recruiting cyclin E-cdk2 complex.
Tamako Nishimura; Mikiko Takahashi; Hon-Song Kim; Hideyuki Mukai; Yoshitaka Ono
Genes to cells : devoted to molecular & cellular mechanisms, 2005年01月, [査読有り] - Protein kinase PKN1 associates with TRAF2 and is involved in TRAF2-NF-kappaB signaling pathway.
Yusuke Gotoh; Kumiko Oishi; Hideki Shibata; Akiko Yamagiwa; Takayuki Isagawa; Tamako Nishimura; Emiko Goyama; Mikiko Takahashi; Hideyuki Mukai; Yoshitaka Ono
Biochemical and biophysical research communications, 2004年02月13日, [査読有り] - Regulation of a mitogen-activated protein kinase kinase kinase, MLTK by PKN.
Mikiko Takahashi; Yusuke Gotoh; Takayuki Isagawa; Tamako Nishimura; Emiko Goyama; Hon-Song Kim; Hideyuki Mukai; Yoshitaka Ono
Journal of biochemistry, 2003年02月, [査読有り]
筆頭著者 - Pulse-chase analysis of protein kinase C.
Mikiko Takahashi; Yoshitaka Ono
Methods in molecular biology (Clifton, N.J.), 2003年, [招待有り]
筆頭著者 - Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.
James E Sillibourne; Diane M Milne; Mikiko Takahashi; Yoshitaka Ono; David W Meek
Journal of molecular biology, 2002年09月27日, [査読有り] - Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.
Mikiko Takahashi; Akiko Yamagiwa; Tamako Nishimura; Hideyuki Mukai; Yoshitaka Ono
Molecular biology of the cell, 2002年09月, [査読有り]
筆頭著者 - PKN delays mitotic timing by inhibition of Cdc25C: possible involvement of PKN in the regulation of cell division.
Misaki K; Mukai H; Yoshinaga C; Oishi K; Isagawa T; Takahashi M; Ohsumi K; Kishimoto T; Ono Y
Proceedings of the National Academy of Sciences of the United States of America, 2001年01月, [査読有り] - Association of immature hypophosphorylated protein kinase cepsilon with an anchoring protein CG-NAP.
Takahashi M; Mukai H; Oishi K; Isagawa T; Ono Y
The Journal of biological chemistry, 2000年11月, [査読有り]
筆頭著者 - Identification and characterization of PKNbeta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKNalpha.
Oishi K; Mukai H; Shibata H; Takahashi M; Ona Y
Biochemical and biophysical research communications, 1999年08月, [査読有り] - Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus.
Takahashi M; Shibata H; Shimakawa M; Miyamoto M; Mukai H; Ono Y
The Journal of biological chemistry, 1999年06月, [査読有り]
筆頭著者 - The role of PKN in the regulation of alphaB-crystallin expression via heat shock transcription factor 1.
Kitagawa M; Mukai H; Takahashi M; Ono Y
Biochemical and biophysical research communications, 1998年11月, [査読有り] - Proteolytic activation of PKN by caspase-3 or related protease during apoptosis.
Takahashi M; Mukai H; Toshimori M; Miyamoto M; Ono Y
Proceedings of the National Academy of Sciences of the United States of America, 1998年09月, [査読有り]
筆頭著者
MISC
- アグリソーム形成における中心体タンパク質PCNTの機能について
KIM Hongsong; 梅原千奈; 大場美嬉; 小林拓巨; 本田小波; 松尾和彦; 高橋美樹子
日本薬学会年会要旨集(Web), 2024年 - CG-NAP/AKAP450はPCM1の細胞内局在を制御することで一次繊毛形成に寄与する
金憲誠; 会田紗也加; 赤江亮祐; 石原賢; 鷺飛鳥; 鈴木捺美; 高橋美樹子
日本分子生物学会年会プログラム・要旨集(Web), 2019年 - ShcとPKCシグナリングのクロストーク:p38MAPキナーゼシグナリングにおけるPKNの機能解析
小野功貴; 向井秀幸; 高橋美樹子
長寿命遺伝子としてのShcシグナリングに関する分子遺伝学的研究 平成14年度 総括・分担研究報告書, 2003年 - アンカリング蛋白質CG-NAPの中心体における機能 微小管形成の開始点であるγ-チューブリンリング複合体(γTuRC)を中心体に繋ぎ止めている可能性について
高橋美樹子; 山際晶子; 西村珠子; 向井秀幸; 小野功貴
生化学, 2002年