疾病に伴う不安

外来看護

潰瘍性大腸炎

臨床看護学

武庫川女子大学大学院　看護学研究科　看護学専攻　博士後期課程修了

日本私学看護系大学協会2024年度看護研究奨励賞

第10回日本炎症性腸疾患学会学術集会優秀ポスター賞

Construction of an explanatory model for quality of life in outpatients with ulcerative colitis
共著, Abstract Introduction: To date, no studies have reported explanatory models of health-related quality of life (HRQoL) in patients with ulcerative colitis. Therefore, this study aimed to examine HRQoL and its related factors in outpatients with ulcerative colitis to construct an explanatory model. Methods: We conducted a cross-sectional survey at a clinic in Japan. The HRQoL was evaluated using the 32-item Inflammatory Bowel Disease Questionnaire. We extracted explanatory variables of HRQoL from demographic, physical, psychological, and social factors reported in previous studies and created a predictive explanatory model. The relationship between explanatory variables and the questionnaire total score was examined using Spearman’s rank correlation coefficient, the Mann–Whitney test, or the Kruskal–Wallis test. We conducted multiple regression and path analyses to examine the effect of explanatory variables on the total score. Results: We included 203 patients. Variables that were associated with the total score were the partial Mayo Score (r = −0.451), treatment side effects (p = 0.004), the Hospital Anxiety Scale-Anxiety score (r = −0.678), the Hospital Anxiety Scale-Depression score (r = −0.528), and the availability of an advisor during difficult times (p = 0.001). The model included the partial Mayo Score, treatment side effects, the Hospital Anxiety Scale-Anxiety score, and the availability of an advisor during difficult times as explanatory variables of the total score that showed the best goodness-of-fit (adjusted R2 = 0.597). The anxiety score exerted the greatest negative effect on the questionnaire total score (β = −0.586), followed by the partial Mayo Score (β = –0.373), treatment side effects (β = 0.121), and availability of an advisor during difficult times (β = −0.101). Conclusion: Psychological symptoms exerted the strongest direct effect on HRQoL in outpatients with ulcerative colitis and mediated the relationship between social, Inflammatory intestinal Disease 8(1),23-33, Karger International, 2023年04月01日, https://doi.org/10.1159/000530455