bisphenol A

Life Science
Animal physiological chemistry, physiology and behavioral biology

Kyushu Institute of Technology, Graduate School of Life Science and Systems Engineering, Department of Brain Science and Engineering

Joint Author, Lead, 22, 1, 29, 33, Jan. 1997, Exist, Research papers (academic journals), Domestic
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Development of a latex immunoturbidimetric assay for the automated measurement of α2 plasmin inhibitor-plasmin complex in human plasma
Joint Author, Fujimoto T, Nakamura K, Nishihira J, Lead, We produced a monoclonal antibody capable of detecting plasmin-plasmin inhibitor complex in plasma, investigated its characteristics, and constructed a measurement system using latex agglutination turbidimetry. Although plasma contains a large amount of plasminogen, a precursor with almost the same structure as plasmin, the measurement system used in this study was hardly affected by it., Semin Thromb Hemost, 25, 6, 551, 556, Dec. 1999
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Prenatal exposure to bisphenol A impairs sexual　differentiation of exploratory behavior and increases depression-like behavior in rats
Joint Author, Fujimoto T, Kubo K, Aou S, Lead, Pregnant rats were exposed to low-dose of bisphenol A (BPA), an environmental hormone, via drinking water. After the rat pups had grown, behavioral tests were conducted. An effect on sex differences in exploratory behavior was observed. Furthermore, BPA exposure showed an increase in depressive-like behavior in a forced swimming test., Brain Res, 1068, 1, 49, 55, Jan. 2006
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Brain strategy for energy saving and environmental preservation.
Joint Author, Aou S, Inoue T, Fujimoto T, Mizuno M, Oomura Y., International Congress Series, 1291, 133, 136, Jun. 2006, Exist, English
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Environmental impacts on brain functions: Low dose effects of bisphenol A during perinatal critical period
Joint Author, Fujimoto T, Kubo K, Aou S, Lead, Rats were exposed to bisphenol A during the fetal and neonatal stages, and then subjected to open field tests after they had grown up, demonstrating that exploratory behavior was a sensitive indicator. , International Congress Series, 1301, 226, 229, Mar. 2007
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Postnatal exposure to low-dose bisphenol A influences various emotional conditions
Joint Author, Fujimoto T, Kubo K, Nishikawa Y, Aou S, Lead, Rats were exposed to bisphenol A exclusively during the neonatal period. The rats offspring were exposed via their mother's breast milk. Sex differences in exploratory behavior in the open field test and increased depressive-like behavior in the forced swimming test were observed. It was suggested that exposure via breast milk also has the same effects as exposure via the placenta., J Toxicol Sci, 38, 4, 539, 546, Aug. 2013
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Brief neonatal handling alters sexually dimorphic behaviors in adult rats
Joint Author, Fujimoto T, Kubo K, Nishikawa Y, Aou S, Lead, It is known that there are various sex differences in the behavior of rats. In the open field test, females score higher in activity and exploratory behavior. However, detection of sex differences in these behaviors is often hindered. We explore the possibility that handling may be one of the factors. , J Integr Neurosci, 13, 1, 61, 70, Mar. 2014
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Prenatal low-dose bisphenol A enhances behavioral responses induced by a predator odor
Joint Author, Fujimoto T, Kubo K, Nishikawa Y, Aou S, Lead, Prenatal exposure to bisphenol A was performed to examine the avoidance behavior of pups in response to predator odors. A new behavioral test device was devised based on the elevated plus maze. Exposed rats significantly avoided the box containing the predator odor. , J Toxicol Sci, 40, 5, 569, 575, Aug. 2015
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College students with high academic performance do not choose front-row seats in the classroom.
Joint Author, Hirano S, Fujimoto T, Inoue H, Uchihashi K, Nishikawa Y., J Osaka Dent Univ, 51, 2, 151, 156, Sep. 2017, Exist, English
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Joint Author, 34, 2, 25, 32, Oct. 2018
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Prenatal bisphenol A exposure is associated with medial amygdala neuron hyperresponsive-ness to predator odor in rats
Joint Author, Fujimoto T, Aou S, Lead, We investigated the brain area responsible for the enhanced avoidance behavior in response to odors in rats exposed to bisphenol A. We targeted the medial amygdala, which is one of the olfactory pathways and also expresses estrogen receptors, to examine the effect of bisphenol A. We used extracellular recording to examine the activity of odor-responsive neurons in response to predator odors., J Toxicol Sci, 43, 9, 531, 536, Oct. 2018
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Prenatal exposure to bisphenol A impairs predator odor-induced fear behavior in young rat offspring
Sole Author, Fujimoto T, Lead, The effects of exposure to bisphenol A were examined in preweaned rats (20 days old). The spontaneous behavior of rats was compared in the presence or absence of predator odor. In the exposure group, "freezing behavior" was suppressed and "grooming behavior" increased. It is thought that the bisphenol A exposure group became accustomed to the stress of the predator odor., Neuroendocrinol Lett, 41, 5, 275, 283, Dec. 2020
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Multiple author, Books (academic), Mar. 2004, Japanese
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