FUJIMOTO TETSUYA
| Faculty of Health and Medical Science,Department of Health and Dietetics | Associate Professor |
Last Updated :2025/06/19
■Profile Information
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■Achievement List
Highest level of education
Paper
- Joint Author, Lead, 22, 1, 29, 33, Jan. 1997, Exist, Research papers (academic journals), Domestic
Url - Development of a latex immunoturbidimetric assay for the automated measurement of α2 plasmin inhibitor-plasmin complex in human plasma
Joint Author, Fujimoto T, Nakamura K, Nishihira J, Lead, We produced a monoclonal antibody capable of detecting plasmin-plasmin inhibitor complex in plasma, investigated its characteristics, and constructed a measurement system using latex agglutination turbidimetry. Although plasma contains a large amount of plasminogen, a precursor with almost the same structure as plasmin, the measurement system used in this study was hardly affected by it., Semin Thromb Hemost, 25, 6, 551, 556, Dec. 1999
Url - Prenatal exposure to bisphenol A impairs sexual differentiation of exploratory behavior and increases depression-like behavior in rats
Joint Author, Fujimoto T, Kubo K, Aou S, Lead, Pregnant rats were exposed to low-dose of bisphenol A (BPA), an environmental hormone, via drinking water. After the rat pups had grown, behavioral tests were conducted. An effect on sex differences in exploratory behavior was observed. Furthermore, BPA exposure showed an increase in depressive-like behavior in a forced swimming test., Brain Res, 1068, 1, 49, 55, Jan. 2006
Url - Brain strategy for energy saving and environmental preservation.
Joint Author, Aou S, Inoue T, Fujimoto T, Mizuno M, Oomura Y., International Congress Series, 1291, 133, 136, Jun. 2006, Exist, English
Url - Environmental impacts on brain functions: Low dose effects of bisphenol A during perinatal critical period
Joint Author, Fujimoto T, Kubo K, Aou S, Lead, Rats were exposed to bisphenol A during the fetal and neonatal stages, and then subjected to open field tests after they had grown up, demonstrating that exploratory behavior was a sensitive indicator. , International Congress Series, 1301, 226, 229, Mar. 2007
Url - Postnatal exposure to low-dose bisphenol A influences various emotional conditions
Joint Author, Fujimoto T, Kubo K, Nishikawa Y, Aou S, Lead, Rats were exposed to bisphenol A exclusively during the neonatal period. The rats offspring were exposed via their mother's breast milk. Sex differences in exploratory behavior in the open field test and increased depressive-like behavior in the forced swimming test were observed. It was suggested that exposure via breast milk also has the same effects as exposure via the placenta., J Toxicol Sci, 38, 4, 539, 546, Aug. 2013
Url - Brief neonatal handling alters sexually dimorphic behaviors in adult rats
Joint Author, Fujimoto T, Kubo K, Nishikawa Y, Aou S, Lead, It is known that there are various sex differences in the behavior of rats. In the open field test, females score higher in activity and exploratory behavior. However, detection of sex differences in these behaviors is often hindered. We explore the possibility that handling may be one of the factors. , J Integr Neurosci, 13, 1, 61, 70, Mar. 2014
Url - Prenatal low-dose bisphenol A enhances behavioral responses induced by a predator odor
Joint Author, Fujimoto T, Kubo K, Nishikawa Y, Aou S, Lead, Prenatal exposure to bisphenol A was performed to examine the avoidance behavior of pups in response to predator odors. A new behavioral test device was devised based on the elevated plus maze. Exposed rats significantly avoided the box containing the predator odor. , J Toxicol Sci, 40, 5, 569, 575, Aug. 2015
Url - College students with high academic performance do not choose front-row seats in the classroom.
Joint Author, Hirano S, Fujimoto T, Inoue H, Uchihashi K, Nishikawa Y., J Osaka Dent Univ, 51, 2, 151, 156, Sep. 2017, Exist, English
Url - Joint Author, 34, 2, 25, 32, Oct. 2018
Url - Prenatal bisphenol A exposure is associated with medial amygdala neuron hyperresponsive-ness to predator odor in rats
Joint Author, Fujimoto T, Aou S, Lead, We investigated the brain area responsible for the enhanced avoidance behavior in response to odors in rats exposed to bisphenol A. We targeted the medial amygdala, which is one of the olfactory pathways and also expresses estrogen receptors, to examine the effect of bisphenol A. We used extracellular recording to examine the activity of odor-responsive neurons in response to predator odors., J Toxicol Sci, 43, 9, 531, 536, Oct. 2018
Url - Prenatal exposure to bisphenol A impairs predator odor-induced fear behavior in young rat offspring
Sole Author, Fujimoto T, Lead, The effects of exposure to bisphenol A were examined in preweaned rats (20 days old). The spontaneous behavior of rats was compared in the presence or absence of predator odor. In the exposure group, "freezing behavior" was suppressed and "grooming behavior" increased. It is thought that the bisphenol A exposure group became accustomed to the stress of the predator odor., Neuroendocrinol Lett, 41, 5, 275, 283, Dec. 2020
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Other Research Achievements
- Exposure to bisphenol A during a later fetal period affect the exploratory behavior and emotions in rats.
Joint Author, Oct. 2004, 34th Society for Neurosci Meeting Abstract. 2004: 616.10. (SanDiego, USA), On the effects of prenatal exposure to bisphenol A, we found a disappearance of sex differences in exploratory behavior in the open field test and an increase in depressive-like behavior in the forced swimming test. - Non-toxic doses of endocrine disrupters impair sexual differentiation of behaviors and enhance depressive behavior in rats.
Joint Author, Jun. 2005, Abstracts of International Behavioral Neuroscience Society. 2005: 53. (Santa Fe, USA) - Prenatal and postnatal exposure to bisphenol A differentially affect exploratory and emotional behavior in rats.
Joint Author, Oct. 2005, 35th Society for Neurosci Meeting Abstract. 2005: 559.16. (Washington DC, USA), Rats were exposed to bisphenol A during the fetal and neonatal periods, and the effects on sex differences in behavior were examined, revealing different patterns of effects in males and females. - 1-Bromopropane prenatal exposure impares sexual differentiation of emotional and sexual behavior in rats.
Joint Author, Jun. 2006, Abstracts of International Behavioral Neuroscience Society. 2006: 47. (Whistler, Canada) - Pre- and postnatal exposure to bisphenol A accelerates behavioral and neuronal responses to stress conditions in rats.
Joint Author, Jun. 2006, Abstracts of International Behavioral Neuroscience Society. 2006: 48. (Whistler, Canada) - Prenatal exposure to 1-Bromopropane impairs sexual differentiation of open-field behavior and suppresses proceptive behavior without affecting spatial learning or hippocampal long-term potentiation in female rats.
Joint Author, Oct. 2006, 36th Society for Neurosci Meeting Abstract. 2006: 152.16. (Atlanta, USA) - Alterations of the avoidance response to predator odor and amygdalar olfactory responses induced by prenatal exposure to bisphenol A in rats.
Joint Author, Oct. 2006, 36th Society for Neurosci Meeting Abstract. 2006: 152.21. (Atlanta, USA), Bisphenol A exposure enhanced avoidance behavior to predator odor and increased the response rate to the odor in neurons in the medial amygdala. - Flow dynamics of classroom seating positions may predict achievement outcome in dental hygiene college students.
Joint Author, Oct. 2014, 44th Society for Neurosci Meeting Abstract [e-Book]. 2014: 23.04 (Washington DC, USA) - Pre-weaning behavioral manners in prenatal bisphenol A treated rats.
Joint Author, Oct. 2015, 45th Society for Neurosci Meeting Abstract [e-Book]. 2015: 161.10 (Chicago, USA), The effects of prenatal exposure to bisphenol A on the behavior of rat pups at 8 and 20 days of age were examined. No significant effects were observed at 8 days of age, but at 20 days of age, the exposed group showed significant hyperactivity. - Evaluation of spontaneous behaviors on an elevated plus maze using bisphenol A exposure model.
Joint Author, Mar. 2019
