Hiromi Saito
| Faculty of Pharmaceutical Sciences,Department of Pharmaceutical Sciences | Professor |
Last Updated :2025/06/19
■Researcher basic information
Field Of Study
■Career
Career
- Apr. 2015 - Present
Teikyo Heisei University, Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences, 教授 - Apr. 2012 - Mar. 2015
Teikyo Heisei University, Faculty of Pharmaceutical Sciences Department of Pharmaceutical Sciences, 准教授 - Apr. 2004 - Mar. 2012
Chiba University, Graduate School of Pharmaceutical Sciences, 講師
Educational Background
■Research activity information
Paper
- Anatase and rutile titanium oxide nanoparticles induce acute kidney injury by coadministration with paraquat, cisplatin or 5-aminosalicylic acid.
H Kamiyama; C Nonaka; H Saitoh; M Ohno; Y Shimizu; K Isoda
Die Pharmazie, 29 Feb. 2024, [Reviewed] - The mechanosensitive channel YbdG from Escherichia coli has a role in adaptation to osmotic up-shock
Shun Amemiya; Hayato Toyoda; Mami Kimura; Hiromi Saito; Hiroshi Kobayashi; Kunio Ihara; Kiyoto Kamagata; Ryuji Kawabata; Setsu Kato; Yutaka Nakashimada; Tadaomi Furuta; Shin Hamamoto; Nobuyuki Uozumi
Journal of Biological Chemistry, Aug. 2019, [Reviewed] - Effect of simvastatin on immune cells under alkaline and acidic conditions.
Fukamachi, T.; Saito, H.; Kobayashi, H.
J. Cancer Sci. Ther., 2015, [Reviewed] - Expression of acidosis-dependent genes in human cancer nests.
Fukamachi, T.; Ikeda, S.; Saito, H.; Tagawa, M.; Kobayashi, H.
Mol. Clin. Oncol, 2014, [Reviewed] - Acidic environments enhance the inhibitory effect of statins on proliferation of synovial cells.
Fukamachi, T.; Wang, X.; Mochizuki Y.; Maruyama C.; Saito, H.; Kobayashi, H.
Int. Immunopharmacol., Jun. 2013, [Reviewed] - Gene expressions for signal transduction under acidic conditions.
Fukamachi, T.; Ikeda, S.; Wang, X.; Saito; H. Tagawa, M.; Kobayashi, H.
Genes, Mar. 2013, [Reviewed] - TCR Signaling via ZAP-70 Induced by CD3 Stimulation is More Active Under Acidic Conditions
Wang, X., Hatatani, K., Sun, Y., Fukamachi, T., Saito, H. and Kobayashi, H.
Journal of Cell Science & Therapy, 2013, [Reviewed] - Respiration and the F1Fo-ATPase Enhance Survival under Acidic Conditions in Escherichia coli
Yirong Sun; Toshihiko Fukamachi; Hiromi Saito; Hiroshi Kobayashi
PLoS ONE, 28 Dec. 2012, [Reviewed] - Adenosine deamination increases the survival under acidic conditions in Escherichia coli
Y. Sun; T. Fukamachi; H. Saito; H. Kobayashi
JOURNAL OF APPLIED MICROBIOLOGY, Apr. 2012, [Reviewed] - ATP requirement for acidic resistance in Escherichia coli.
Sun, Y.; Fukamachi, T.; Saito, H.; Kobayashi, H.
J. Bacteriol., Jun. 2011, [Reviewed] - Expression and Activity of Kdp under Acidic Conditions in Escherichia coli
Yan Hongwei; Fukamachi Toshihiko; Saito Hiromi; Kobayashi Hiroshi
Biological and Pharmaceutical Bulletin, 2011, [Reviewed] - The Role of OmpC and OmpF in Acidic Resistance in Escherichia coli
Bekhit Amany; Fukamachi Toshihiko; Saito Hiromi; Kobayashi Hiroshi
Biological and Pharmaceutical Bulletin, 2011, [Reviewed] - Tumor specific low pH environments enhance the cytotoxicity of lovastatin and cantharidin.
Fukamachi, T.; Chiba, Y.; Wang, X.; Saito, H.; Tagawa, M.; Kobayashi, H.
Cancer Lett., Nov. 2010, [Reviewed] - HU participates in expression of a specific set of genes required for growth and survival at acidic pH in Escherichia coli.
Bi, H.; Sun, L.; Fukamachi, T.; Saito, H.; Kobayashi, H.
Curr. Microbiol., May 2009, [Reviewed] - Extracellular acidic environments induce phosphorylation of ZAP-70 in Jurkat T cells.
Hirata, S.; Fukamachi, T.; Sakano, H.; Tarora, A.; Saito, H.; Kobayashi, H.
Immunol. Lett., Jan. 2008, [Reviewed] - Requirement of an I kappa B-beta COOH terminal region protein for acidic-adaptation in CHO cells
QZ Lao; T Fukamachi; H Saito; O Kuge; M Nishijima; H Kayashi
JOURNAL OF CELLULAR PHYSIOLOGY, Apr. 2006, [Reviewed] - OmpC and OmpF are required for growth under hyperosmotic stress above pH 8 in Escherichia coli
M Kaeriyama; K Machida; A Kitakaze; H Wang; Q Lao; T Fukamachi; H Saito; H Kobayashi
LETTERS IN APPLIED MICROBIOLOGY, Mar. 2006, [Reviewed] - CTIB (C-terminus protein of I kappa B-beta): A novel factor required for acidic adaptation
Fukamachi, T.; Lao, Q.; Okamura, S.; Saito, H.; Kobayashi, H.
Adv. Exp. Med. Biol., 2006 - Carbon dioxide increases acid resistance in Escherichia coli
L. Sun; T. Fukamachi; H. Saito; H. Kobayashi
LETTERS IN APPLIED MICROBIOLOGY, Jun. 2005, [Reviewed] - An I kappa B-beta COOH terminal region protein is essential for the proliferation of CHO cells under acidic stress
QZ Lao; L Kuge; T Fukamachi; F Kakegawa; H Saito; M Nishijima; H Kobayashi
JOURNAL OF CELLULAR PHYSIOLOGY, Apr. 2005, [Reviewed] - Expression of chaA, a sodium ion extrusion system of Escherichia coli, is regulated by osmolarity and pH
T Shijuku; T Yamashino; H Ohashi; H Saito; T Kakegawa; M Ohta; H Kobayashi
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Dec. 2002, [Reviewed] - Membrane-bound ATPase contributes to hop resistance of Lactobacillus brevis
K Sakamoto; HW van Veen; H Saito; H Kobayashi; WN Konings
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Nov. 2002, [Reviewed] - Different proteins are phosphorylated under acidic environments in Jurkat cells
T Fukamachi; H Saito; T Kakegawa; H Kobayashi
IMMUNOLOGY LETTERS, Jun. 2002, [Reviewed] - Rapamycin induces binding activity to the terminal oligopyrimidine tract of ribosomal protein mRNA in rats
T Kakegawa; M Ito; A Hayakawa; M Matsuda; S Tamura; H Saito; RL Kaspar; H Kobayashi
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Jun. 2002, [Reviewed] - Expression of sodium/proton antiporter NhaA at various pH values in Escherichia coli
T Shijuku; H Saito; T Kakegawa; H Kobayashi
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Nov. 2001, [Reviewed] - Ethylene glycol bis(beta-aminoethyl ether)-N,N,N ',N '-tetraacetic acid (EGTA) inhibits the growth of Escherichia coli at alkaline pH
Y Arakawa; T Saito; H Saito; T Kakegawa; H Kobayashi
JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY, Jun. 2000, [Reviewed] - Expression of outer membrane proteins in Escherichia coli growing at acid pH
M Sato; K Machida; E Arikado; H Saito; T Kakegawa; H Kobayashi
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, Mar. 2000, [Reviewed] - Enzyme level of enterococcal F1F0-ATPase is regulated by pH at the step of assembly
E Arikado; H Ishihara; T Ehara; C Shibata; H Saito; T Kakegawa; K Igarashi; H Kobayashi
EUROPEAN JOURNAL OF BIOCHEMISTRY, Jan. 1999, [Reviewed] - Cloning and expression analysis of a cDNA coding for a dexamethasone-inducible cytochrome P450 in Xenopus laevis liver
H Ohi; E Sugata; Y Fujita; H Saito; K Saguchi; N Murayama; S Higuchi
BIOCHEMISTRY AND MOLECULAR BIOLOGY INTERNATIONAL, Jul. 1998, [Reviewed] - pH dependence of the function of sodium ion extrusion systems in Escherichia coli
T Sakuma; N Yamada; H Saito; T Kakegawa; H Kobayashi
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS, Mar. 1998, [Reviewed] - Growth of an Escherichia coli mutant deficient in respiration
L Futatsugi; H Saito; T Kakegawa; H Kobayashi
FEMS MICROBIOLOGY LETTERS, Nov. 1997, [Reviewed] - Purification and characterization of a cytochrome P450 from liver microsomes of Xenopus laevis
H Saito; H Ohi; E Sugata; N Murayama; Y Fujita; S Higuchi
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, Sep. 1997, [Reviewed]
Lead - Cloning and sequence analysis of a Bothrops jararaca cDNA encoding a precursor of seven bradykinin-potentiating peptides and a C-type natriuretic peptide
N Murayama; MAF Hayashi; H Ohi; LAF Ferreira; VV Hermann; H Saito; Y Fujita; S Higuchi; BL Fernandes; T Yamane; ACM DeCamargo
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Feb. 1997, [Reviewed] - Purification and characterization of a hemocyte proteinase of Sarcophaga, possibly participating in elimination of foreign substances.
Saito, H.; Kurata, S.; Natori, S.
EUROPEAN JOURNAL OF BIOCHEMISTRY, Nov. 1992, [Reviewed]
Lead - The 29-kDa hemocyte proteinase dissociates fat body at metamorphosis of Sarcophaga.
Kurata, S.; Saito, H.; Natori, S.
DEVELOPMENTAL BIOLOGY, Sep. 1992, [Reviewed] - Purification of a 29-kDa hemocyte proteinase of Sarcophaga peregrina.
Kurata, S.; Saito, H.; Natori, S.
EUROPEAN JOURNAL OF BIOCHEMISTRY, Mar. 1992, [Reviewed] - Participation of hemocyte proteinase in dissociation of the fat body on pupation of Sarcophaga peregrina (flesh fly).
Kurata, S.; Saito, H.; Natori, S.
INSECT BIOCHEMISTRY, 1990, [Reviewed] - Molecular cloning of cDNA for sarcocystatin A and analysis of the expression of the sarcocystatin A gene during development of Sarcophaga peregrina.
Saito, H.; Suzuki, T.; Ueno, K.; Kubo, T.; Natori, S.
BIOCHEMISTRY, Feb. 1989, [Reviewed]
Lead
MISC
- Reviving Previous Therapeutics by Recombinant Anaerobic Bifidobacteria
Taira, I.; Taira, Y.; Kato, M.; Shimizu, Y.; Isoda, K.; Saitou, H.; Ishida, I.
Biomedical Journal of Scientific & Technical Research, 09 Jan. 2019 - Bacterial responses to alkaline stress.
Saito, H.; Kobayashi, H.
Science Progress, 2003 - Bacterial strategies to inhabit acidic environments.
Kobayashi, H.; Saito, H.; Kakegawa, T.
JOURNAL OF GENERAL AND APPLIED MICROBIOLOGY, Oct. 2000 - Cation movements at alkaline pH in bacteria growing without respiration.
Hiroshi Kobayashi; Hiromi Saito; Lui Futatsugi; Tomohito Kakegawa
Bacterial responses to pH., 1999
Research Themes
