Ryohei Yanoshita
Faculty of Pharmaceutical Sciences,Department of Pharmaceutical Sciences | Professor |
Last Updated :2025/06/19
■Researcher basic information
■Career
■Research activity information
Paper
- Distinguishing two distinct types of salivary extracellular vesicles: a potential tool for understanding their pathophysiological roles.
Yuko Ogawa; Yuri Miura; Mamoru Ikemoto; Atsushi Ohnishi; Yoshikuni Goto; Kazuma Aoki; Yuki Motokurumada; Yoshihiro Akimoto; Tamao Endo; Masafumi Tsujimoto; Ryohei Yanoshita
Frontiers in molecular biosciences, 2024 - Stability of human salivary extracellular vesicles containing dipeptidyl peptidase IV under simulated gastrointestinal tract conditions
Yuko Ogawa; Yoshihiro Akimoto; Mamoru Ikemoto; Yoshikuni Goto; Anna Ishikawa; Sakura Ohta; Yumi Takase; Hayato Kawakami; Masafumi Tsujimoto; Ryohei Yanoshita
Biochemistry and Biophysics Reports, Sep. 2021 - ヒト唾液由来exosomeの表面分子の結合状態および免疫活性化の制御への関与
小川 裕子; 粂田 奈宝子; 後藤 芳邦; 辻本 雅文; 秋元 義弘; 川上 速人; 矢ノ下 良平
日本唾液腺学会誌, Nov. 2018 - Exosome-associated Shiga toxin 2 is released from cells and causes severe toxicity in mice
Miho Watanabe-Takahashi; Shinji Yamasaki; Masayuki Murata; Fumi Kano; Jun Motoyama; Jyoji Yamate; Jumpei Omi; Waka Sato; Hirofumi Ukai; Kentaro Shimasaki; Masaya Ikegawa; Miwa Tamura-Nakano; Ryohei Yanoshita; Yuri Nishino; Atsuo Miyazawa; Yasuhiro Natori; Noriko Toyama-Sorimachi; Kiyotaka Nishikawa
Scientific Reports, 17 Jul. 2018, [Reviewed] - Contribution of the exosome-associated form of secreted endoplasmic reticulum aminopeptidase 1 to exosome-mediated macrophage activation.
Goto Y; Ogawa Y; Tsumoto H; Miura Y; Nakamura TJ; Ogawa K; Akimoto Y; Kawakami H; Endo T; Yanoshita R; Tsujimoto M
Biochimica et biophysica acta. Molecular cell research, Jun. 2018, [Reviewed] - Hepatotoxicity, nephrotoxicity, and drug/chemical interaction toxicity of platinum nanoparticles in mice
Katsuhiro Isoda; T. Daibo; K. Yushina; Y. Yoshioka; Y. Tsutsumi; Y. Akimoto; H. Kawakami; Y. Taira; I. Taira; R. Yanoshita; T. Nishimura; I. Ishida
Pharmazie, 2017 - Characterization of membrane integrity and morphological stability of human salivary exosomes
Nahoko Kumeda; Yuko Ogawa; Yoshihiro Akimoto; Hayato Kawakami; Masafumi Tsujimoto; Ryohei Yanoshita
Biological and Pharmaceutical Bulletin, 2017, [Reviewed] - Next-Generation Sequencing of Protein-Coding and Long Non-protein-Coding RNAs in Two Types of Exosomes Derived from Human Whole Saliva.
Ogawa Y; Tsujimoto M; Yanoshita R
Biological & pharmaceutical bulletin, 2016, [Reviewed] - ヒト唾液エキソソームによるマクロファージの活性化
小川 裕子[池本]; 粂田 奈宝子; 後藤 芳邦; 池本 守; 辻本 雅文; 矢ノ下 良平
日本生化学会大会プログラム・講演要旨集, Oct. 2014 - 唾液エキソソームによるRAW264.7細胞の活性化
粂田 奈宝子; 高橋 琢也; 井筒 博紀; 鈴木 麻衣子; 後藤 芳邦; 小川 裕子; 辻本 雅文; 矢ノ下 良平
日本薬学会年会要旨集, Mar. 2013 - Small RNA transcriptomes of two types of exosomes in human whole saliva determined by next generation sequencing.
Ogawa Y; Taketomi Y; Murakami M; Tsujimoto M; Yanoshita R
Biological & pharmaceutical bulletin, 2013, [Reviewed] - Selective accumulation of a novel antimalarial rhodacyanine derivative, SSJ-127, in an organelle of Plasmodium berghei
Mayumi Ikegami-Kawai; Chika Arai; Yuko Ogawa; Ryohei Yanoshita; Masataka Ihara
BIOORGANIC & MEDICINAL CHEMISTRY, Nov. 2010, [Reviewed] - Molecular cloning and characterization of ecto-5'-nucleotidase from the venoms of Gloydius blomhoffi.
Ogawa Y; Murayama N; Yanoshita R
Toxicon : official journal of the International Society on Toxinology, Sep. 2009, [Reviewed] - Exosome-like vesicles with dipeptidyl peptidase IV in human saliva.
Ogawa Y; Kanai-Azuma M; Akimoto Y; Kawakami H; Yanoshita R
Biological & pharmaceutical bulletin, Jun. 2008, [Reviewed] - Exosome-like vesicles in Gloydius blomhoffii blomhoffii venom.
Ogawa Y; Kanai-Azuma M; Akimoto Y; Kawakami H; Yanoshita R
Toxicon : official journal of the International Society on Toxinology, May 2008, [Reviewed] - Characterization and cDNA cloning of aminopeptidase A from the venom of Gloydius blomhoffi brevicaudus.
Ogawa Y; Murayama N; Fujita Y; Yanoshita R
Toxicon, 2007, [Reviewed] - Structural analysis of the interaction between Shiga toxin B subunits and linear polymers bearing clustered globotriose residues
M Watanabe; K Igai; K Matsuoka; A Miyagawa; T Watanabe; R Yanoshita; Y Samejima; D Terunuma; Y Natori; K Nishikawa
INFECTION AND IMMUNITY, Mar. 2006, [Reviewed] - Molecular cloning of the major lethal toxins from two kraits (Bungarus flaviceps and Bungarus candidus).
Yanoshita R; Ogawa Y; Murayama N; Omori-Satoh T
Toxicon, 2006 - Characterization and cDNA cloning of dipeptidyl peptidase IV from the venom of Gloydius blomhoffi brevicaudus.
Ogawa Y; Mamura Y; Murayama N; Yanoshita R
Comp Biochem Physiol B Biochem Mol Biol., 2006 - Oral therapeutic agents with highly clustered globotriose for treatment of Shiga toxigenic Escherichia coli infections
M Watanabe; K Matsuoka; E Kita; K Igai; N Higashi; A Miyagawa; T Watanabe; R Yanoshita; Y Samejima; D Terunuma; Y Natori; K Nishikawa
JOURNAL OF INFECTIOUS DISEASES, Feb. 2004, [Reviewed] - Complete amino acid sequence and phylogenetic analysis of a long-chain neurotoxin from the venom of the African banded water cobra, Boulengerina annulata.
Ogawa Y; Yanoshita R; Kuch U
Toxicon, 2004 - Isolation, Toxicity and Amino Terminal Sequences of Three Major Neurotoxins in the Venom of Malayan Krait (Bungarus candidus) from Thailand.
Khow, O; Chanhome, L; Omori-Satoh, T; Ogawa, Y; Yanoshita, R
J Biochem (Tokyo), 2003 - Activated mast cells release extracellular type platelet-activating factor acetylhydrolase that contributes to autocrine inactivation of platelet-activating factor
K Nakajima; M Murakami; R Yanoshita; Y Samejima; K Karasawa; M Setaka; S Nojima; Kudo, I
JOURNAL OF BIOLOGICAL CHEMISTRY, Aug. 1997, [Reviewed] - GUINEA-PIG BONE-MARROW CELLS TREATED WITH PLATELET-ACTIVATING-FACTOR GENERATE FACTOR(S) WHICH AFFECTS THEIR DNA-SYNTHESIS AND MICROBICIDAL ACTIVITY
KUDO, I; T KATO; H HAYASHI; R YANOSHITA; K IKIZAWA; H UDA; K INOUE
LIPIDS, Dec. 1991, [Reviewed]
MISC
- LPS-binding proteins in human salivary extracellular vesicles regulate the activation of macrophages.
小川裕子; 三浦ゆり; 後藤芳邦; 池本守; 秋元義弘; 遠藤玉夫; 矢ノ下良平
日本薬学会年会要旨集(Web), 2023 - アミノペプチダーゼに着目したヒト唾液由来細胞外小胞の性状解析
小川 裕子; 池本 守; 三浦 ゆり; 津元 裕樹; 遠藤 玉夫; 本車田 悠希; 堤 周平; 長島 茉央; 松岡 千裕; 原 紅音; 秋元 義弘; 川上 速人; 矢ノ下 良平
日本薬学会年会要旨集, Mar. 2022 - Specification of extracellular vesicles characterized by their membrane proteins, APN/mucin1 or DPP IV/CD9
小川裕子; 三浦ゆり; 大西敦; 後藤芳邦; 青木一真; 池本守; 本車田悠希; 堤周平; 長島茉央; 廣谷莉花; 武井亮太朗; 秋元義弘; 遠藤玉夫; 矢ノ下良平
日本唾液腺学会誌, 2022 - Proteomic Analysis of Two Types of Exosomes in Human Whole Saliva
Yuko Ogawa; Yuri Miura; Akira Harazono; Masami Kanai-Azuma; Yoshihiro Akimoto; Hayato Kawakami; Teruhide Yamaguchi; Tosifusa Toda; Tamao Endo; Masayoshi Tsubuki; Ryohei Yanoshita
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Jan. 2011 - ヘビ毒の膜結合性酵素の性状解析とcDNAクローニング
小川 裕子; 村山 信浩; 矢ノ下 良平
日本薬学会年会要旨集, Mar. 2008 - cDNA cloning of bradykinin-potentiating peptides-C-type natriuretic peptide precursor, and characterization of the novel peptide Leu3-blomhotin from the venom of Agkistrodon blomhoffi
N Murayama; GH Michel; R Yanoshita; Y Samejima; K Saguchi; H Ohi; Y Fujita; S Higuchi
EUROPEAN JOURNAL OF BIOCHEMISTRY, Jul. 2000 - Blomhotin: a novel peptide with smooth muscle contractile activity identified in the venom of Agkistrodon halys blomhoffii
R Yanoshita; A Kasuga; S Inoue; K Ikeda; Y Samejima
TOXICON, Dec. 1999 - Inhibition of LysoPAF acetyltransferase activity by components of licorice root
S Nagumo; A Fukuju; M Takayama; H Nagai; R Yanoshita; Y Samejima
BIOLOGICAL & PHARMACEUTICAL BULLETIN, Oct. 1999 - PREFERENTIAL HYDROLYSIS OF PHOSPHATIDYLETHANOLAMINE IN RAT ISCHEMIC HEART HOMOGENATES DURING IN-VITRO INCUBATION
R KIKUCHIYANOSHITA; R YANOSHITA; KUDO, I; H ARAI; T TAKAMURA; K NOMOTO; K INOUE
JOURNAL OF BIOCHEMISTRY, Jul. 1993 - PAFの薬理作用(共著)
治療学, 1992 - HYDROLYSIS OF PLATELET ACTIVATING FACTOR AND ITS METHYLATED ANALOGS BY ACETYLHYDROLASES
R YANOSHITA; KUDO, I; K IKIZAWA; HW CHANG; S KOBAYASHI; M OHNO; S NOJIMA; K INOUE
JOURNAL OF BIOCHEMISTRY, May 1988
Research Themes
- Mechanism of mucosal immunity activation by exosome
Grant-in-Aid for Scientific Research (C)
Teikyo Heisei University
21 Oct. 2016 - 31 Mar. 2019 - Molecular mechanism and regulation of immune activation cascade by aminopeptidase contained exosome.
Grant-in-Aid for Scientific Research (C)
Teikyo Heisei University
01 Apr. 2013 - 31 Mar. 2016 - exosome