Takafumi Nakano
| Faculty of Pharmaceutical Sciences,Department of Pharmaceutical Sciences | Instructor |
Last Updated :2025/06/19
■Researcher basic information
■Career
Career
Educational Background
■Research activity information
Paper
- Hepatitis C virus core protein triggers abnormal porphyrin metabolism in human hepatocellular carcinoma cells
Takafumi Nakano; Kyoji Moriya; Kazuhiko Koike; Toshiharu Horie
PLoS ONE, 01 Jun. 2018, [Reviewed]
Lead, Corresponding - Mitochondrial iron accumulation exacerbates hepatic toxicity caused by hepatitis C virus core protein
Shuichi Sekine; Konomi Ito; Haruna Watanabe; Takafumi Nakano; Kyoji Moriya; Yoshizumi Shintani; Hajime Fujie; Takeya Tsutsumi; Hideyuki Miyoshi; Hidetake Fujinaga; Seiko Shinzawa; Kazuhiko Koike; Toshiharu Hone
TOXICOLOGY AND APPLIED PHARMACOLOGY, Feb. 2015, [Reviewed] - Ezrin regulates the expression of Mrp2/Abcc2 and Mdr1/Abcb1 along the rat small intestinal tract.
Takafumi Nakano; Shuichi Sekine; Kousei Ito; Toshiharu Horie
American journal of physiology. Gastrointestinal and liver physiology, Dec. 2013, [Reviewed]
Lead - Correlation between Apical Localization of Abcc2/Mrp2 and Phosphorylation Status of Ezrin in Rat Intestine
Takafumi Nakano; Shuichi Sekine; Kousei Ito; Toshiharu Horie
DRUG METABOLISM AND DISPOSITION, Jul. 2009, [Reviewed]
Lead
MISC
- Investigation of the mechanism of cytoprotection by heme oxygenase-1 against staurosporine-induced cytotoxicity
中埜貴文; 高橋純香; 野内匠; 水間俊
日本薬学会年会要旨集(Web), 2024 - Investigation of the mechanism of cytoprotection by heme oxygenase-1 against tamoxifen-induced cytotoxicity
中埜貴文; 嶋津杏那; 渡邉雄基; 水間俊
日本薬学会年会要旨集(Web), 2023 - Heme oxygenase-1 attenuate tamoxifen induced cytotoxicity in a heme catabolism-independent manner
中埜貴文; 澤井貴則; 菅原康矢; 水間俊
日本薬学会年会要旨集(Web), 2022 - The disorders of heme/porphyrin biosynthesis induced by methionine-choline-deficiency in mouse hepatocytes
中埜貴文; 斎藤碧; 水間俊
日本薬学会年会要旨集(Web), 2021 - The change in heme synthesis pathway in the hepatocyte treated with methionine-choline-deficient medium
中埜貴文; 佐和田優弥; 宮本裕吏; 水間俊; 堀江利治
日本薬学会年会要旨集(Web), 2020 - 小腸における薬物トランスポーターMRP2/ABCC2,MDR1/ABCB1の細胞膜局在制御機構の解明
関根秀一; 中埜貴文; 伊藤晃成; 堀江利治
生体膜と薬物の相互作用シンポジウム講演要旨集, 2012 - Ezrin has a key role in the expression profile of MRP2 and MDR1 along intestinal tract
Shuichi Sekine; Kousei Ito; Takafumi Nakano; Toshiharu Horie
DRUG METABOLISM REVIEWS, Aug. 2010 - 小腸におけるMrp2、Mdr1発現部位差とezrinの発現、リン酸化状態の部位差との関連
中埜 貴文; 関根 秀一; 伊藤 晃成; 堀江 利治
薬剤学: 生命とくすり, Apr. 2010, [Reviewed] - PHOSPHORYLATION STATUS OF EZRIN REGULATES MRP2 LOCALIZATION IN RAT INTESTINE
Takafumi Nakano; Shuichi Sekine; Kousei Ito; Toshiharu Horie
DRUG METABOLISM REVIEWS, 2007
Affiliated academic society
Research Themes
- Involvement of heme metabolic disorders in hepatocytes in the development of nonalcoholic steatohepatitis.
Grant-in-Aid for Scientific Research (C)
Teikyo Heisei University
Apr. 2019 - Mar. 2022 - Investigation of the link between hepatitis C and porphyria cutanea tarda
Grant-in-Aid for Young Scientists (B)
Teikyo Heisei University
Apr. 2015 - Mar. 2018 - Analysis of idiosyncratic drug toxicity using mitochondria isolated from an animal model of metabolic syndrome
Grant-in-Aid for Challenging Exploratory Research
Teikyo Heisei University
Apr. 2014 - Mar. 2016
