赤木 祐介
| 薬学部 薬学科 | 講師 |
Last Updated :2025/10/07
■研究者基本情報
■研究活動情報
論文
- Side-Chain Fluorine Engineering of Vitamin D<sub>3</sub> Derivatives for VDR-Silent SREBP Inhibitors
Fumihiro Kawagoe; Sayuri Mototani; Tomofumi Yatsu; Yasushi Takemoto; Yusuke Akagi; Toshie Fujishima; Yoshiki Miyata; Motonari Uesugi; Atsushi Kittaka
Chemical and Pharmaceutical Bulletin, 2025年09月20日, ［査読有り］ - Synthesis and in Vitro Cytotoxicity Evaluation of Jadomycins
Erika Iwasaki; Yoshimi Shimizu; Yusuke Akagi; Toshiya Komatsu
Chemical and Pharmaceutical Bulletin, 2023年09月01日, ［査読有り］ - Total synthesis of jadomycins A, B, and l-digitoxosyl-phenanthroviridin
Yusuke Akagi; Yuta Mori; Yudai Sato; Erika Iwasaki; Toshiya Komatsu
Tetrahedron Letters, 2022年07月, ［査読有り］
筆頭著者, 責任著者 - Discovery of a Vitamin D Receptor-Silent Vitamin D Derivative That Impairs Sterol Regulatory Element-Binding Protein In Vivo
Fumihiro Kawagoe; Aileen Mendoza; Yuki Hayata; Lisa Asano; Kenjiro Kotake; Sayuri Mototani; Satoshi Kawamura; Shigeyuki Kurosaki; Yusuke Akagi; Yasushi Takemoto; Kazuo Nagasawa; Hayato Nakagawa; Motonari Uesugi; Atsushi Kittaka
Journal of Medicinal Chemistry, 2021年05月13日, ［査読有り］ - Total Synthesis of Phenanthroviridin Aglycon and Its Analog
Yusuke Akagi; Kohei Harasawa; Toshiya Komatsu
Asian Journal of Organic Chemistry, 2021年05月, ［査読有り］
筆頭著者, 責任著者 - Palladium-catalyzed arylation of 1,4-naphthoquinones with aryl iodides and its synthetic application to the benzo[b]phenanthridine skeleton
Akagi, Y.; Komatsu, T.
Tetrahedron Letters, 2020年, ［査読有り］
筆頭著者, 責任著者 - Palladium-Catalyzed β-Arylation of Cyclic α,β-Unsaturated O-Methyl Oximes with Aryl Iodides
Akagi, Y.; Fukuyama, S.; Komatsu, T.
Chemical & pharmaceutical bulletin, 2020年, ［査読有り］
筆頭著者, 責任著者 - Synthetic Chemical Probes That Dissect Vitamin D Activities
Nagata, A.; Akagi, Y.; Asano, L.; Kotake, K.; Kawagoe, F.; Mendoza, A.; Masoud, S.S.; Usuda, K.; Yasui, K.; Takemoto, Y.; Kittaka, A.; Nagasawa, K.; Uesugi, M.
ACS Chemical Biology, 2019年, ［査読有り］ - Stereoselective Synthesis of Four Calcitriol Lactone Diastereomers at C23 and C25
Nagata, A.; Akagi, Y.; Masoud, S.S.; Yamanaka, M.; Kittaka, A.; Uesugi, M.; Odagi, M.; Nagasawa, K.
Journal of Organic Chemistry, 2019年, ［査読有り］ - Synthetic studies of (23S,25R)-1α,25-dihydroxyvitamin D
3 26,23-lactone (calcitriol lactone) and its derivatives
Akagi, Y.; Nagata, A.; Odagi, M.; Nagasawa, K.
Journal of Steroid Biochemistry and Molecular Biology, 2018年, ［査読有り］ - A-Ring Synthons of 19-Nor Type Vitamin D Derivatives
Akagi, Y.; Yasui, K.; Nagasawa, K.
Journal of Steroid Biochemistry and Molecular Biology, 2017年, ［査読有り］ - Synthesis of diastereomers of 1,3-cis-25-dihydroxy-19-norvitamin D
3
Usuda, K.; Biswas, T.; Yamaguchi, T.; Akagi, Y.; Yasui, K.; Uesugi, M.; Shimizu, I.; Hosokawa, S.; Nagasawa, K.
Chemical and Pharmaceutical Bulletin, 2016年, ［査読有り］ - Synthesis of 24,24-difluoro-1,3-cis-25-dihydroxy-19-norvitamin D
3 derivatives and evaluation of their vitamin D receptor-binding affinity
Biswas, T.; Akagi, Y.; Usuda, K.; Yasui, K.; Shimizu, I.; Okamoto, M.; Uesugi, M.; Hosokawa, S.; Nagasawa, K.
Biological and Pharmaceutical Bulletin, 2016年, ［査読有り］ - Synthesis of 1 α- and 1 β-amino-25-hydroxyvitamin D
3
Akagi, Y.; Usuda, K.; Tanami, T.; Yasui, K.; Asano, L.; Uesugi, M.; Nagasawa, K.
Asian Journal of Organic Chemistry, 2016年, ［査読有り］ - Synthesis of jadomycin A and related jadomycin aglycons: Structural re-examination of jadomycins S and T may be needed
Tajima, T.; Akagi, Y.; Kumamoto, T.; Suzuki, N.; Ishikawa, T.
Tetrahedron Letters, 2012年, ［査読有り］ - Synthetic studies on jadomycins: synthesis of dimethyljadomycin A
Akagi, Y.; Yamada, S.-i.; Etomi, N.; Kumamoto, T.; Nakanishi, W.; Ishikawa, T.
Tetrahedron Letters, 2010年, ［査読有り］
筆頭著者
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