Constraint-induced movement therapy (CI療法)—特集 脳卒中片麻痺 : 理学療法の歩みと最新の取り組み ; 脳卒中片麻痺の回復・改善促通に寄与する治療や考え方
Jun. 2025, [Invited]

Relationship between the amount of physical activity and brain structure in patients with chronic stroke
Tomoyoshi Kobari; Takashi Murayama; Yumi Ikeda
Neurological Research, 14 Jun. 2024, [Reviewed]

Effects of a treatment program based on constraint-induced movement therapy for the lower extremities on gait and balance in chronic stroke: a 6-month follow-up pilot study.
Tomoyoshi Kobari; Takashi Murayama; Kazuhiro Matsuzawa; Katsuya Sakai
International journal of rehabilitation research., 01 Jun. 2023, [Reviewed]
Constraint-induced movement therapy (CIMT) for the lower extremities CIMT (LE-CIMT) has been shown feasible and promising but the long-term outcomes remain uncertain. In this pilot study, we recruited eight participants with chronic stroke from our facility for persons with disabilities to determine changes in gait and balance throughout an extended treatment program based on the principles of LE-CIMT. The program consisted of a run-in phase (3 weeks), LE-CIMT phase (3 weeks), and maintenance phase (6 months). In the LE-CIMT phase (3.5 h/day, 5 days/week, 3 weeks), the participants received task-oriented training (3 h) and transfer package training (30 min). The maintenance phase (30 min/day, 2-3 times/week, 6 months) included a transfer package and conventional training. The assessments were performed in the beginning and after each phase using the Fugl-Meyer Assessment, 6-min walk test (6MWT), Berg Balance Scale (BBS), and 10-m walk test from which walking speed, cadence, and stride length were derived. Overall, 6MWT, BBS, walking speed, and cadence improved significantly over time (analysis of variance P  < 0.001). When comparing the results from before to after the LE-CIMT phase, 6MWT, BBS, walking speed, and cadence improved significantly ( P  = 0.002 to 0.022). At the end of the 6-month maintenance phase, further improvements relative to the after LE-CIMT phase were found for 6MWT, walking speed, and cadence ( P  = 0.002 to 0.034). These pilot results suggest that an extended treatment program based on the principles of LE-CIMT can improve balance and more so walking in the chronic phase of stroke.

障害者支援施設における施設入所支援で機能訓練事業を利用した慢性期脳卒中片麻痺者の歩行能力と移動範囲の変化
Mar. 2023, [Reviewed]

【臨床に活かすニューロリハビリテーション】臨床に活かすニューロリハビリテーション 運動麻痺
Apr. 2022, [Invited]

Anatomical Increased/Decreased Changes in the Brain Area Following Individuals with Chronic Traumatic Complete Thoracic Spinal Cord Injury.
Takashi Murayama; Kousuke Takahama; Kazumasa Jinbo; Tomoyoshi Kobari
Physical therapy research, 2021, [Reviewed]
OBJECTIVES: This study aimed to investigate anatomical changes in the brain following chronic complete traumatic thoracic spinal cord injury (ThSCI) using voxel-based morphometry (VBM). That is, it attempted to examine dynamic physical change following thoracic injury and the presence or absence of regions with decreased and increased changes in whole brain volume associated with change in the manner of how activities of daily living are performed. METHODS: Twelve individuals with chronic traumatic complete ThSCI (age; 21-63 years, American Spinal Injury Association Impairment Scale; grade C-D) participated in this study. VBM was used to investigate the regions with increased volume and decreased volume in the brain in comparison with healthy control individuals. RESULTS: Decreases in volume were noted in areas associated with motor and somatosensory functions, including the right paracentral lobule (PCL)-the primary motor sensory area for lower limbs, left dorsal premotor cortex, and left superior parietal lobule (SPL). Furthermore, increased gray matter volume was noted in the primary sensorimotor area for fingers and arms, as well as in higher sensory areas. CONCLUSIONS: Following SCI both regions with increased volume and regions with decreased volume were present in the brain in accordance with changes in physical function. Using longitudinal observation, anatomical changes in the brain may be used to determine the rehabilitation effect by comparing present cases with cases with cervical SCI or cases with incomplete palsy.

慢性期脳卒中者の下肢に対する健側非拘束下modified constraint-induced movement therapyの効果
Sep. 2019, [Reviewed]

【脳卒中患者の上肢に対する理学療法up to date】脳卒中患者の上肢に対するCI療法の効果と経過
Jul. 2019, [Invited]

慢性期脳卒中片麻痺例に対するCI療法のコンセプトを応用した下肢集中訓練の試み
Aug. 2018, [Reviewed]

回復期重度片麻痺一例に対する手指装具療法を併用したmodified constraint-induced movement therapyの長期効果
Mar. 2017, [Reviewed]

若年脳性麻痺者の歩行時における身体活動量計の信頼性と妥当性の検証
2025

慢性期脳卒中片麻痺者の身体活動量が脳の構造と機能結合に及ぼす影響
2022

慢性期脳卒中片麻痺者に対する下肢CI療法が身体機能と脳活動動態に及ぼす影響　　　　　　　　　　　　　　　
Oct. 2021

障害者支援施設における施設入所支援で機能訓練事業を利用した慢性期脳卒中片麻痺者の歩行能力と移動範囲の変化
2021

脳卒中重度上肢麻痺例に対する修正CI療法の実践と長期経過について　　　　　　　　　　　　　　　
Aug. 2019

下肢麻痺に対するCI療法をベースとした集中訓練により身体機能と自己効力感が向上した慢性期脳卒中片麻痺症例　　　　　　　　　　　　　　　
Aug. 2019

上肢CI療法後に生じた脳解剖学的変化　　　　　　　　　　　　　　　
May 2019

重度片麻痺の失語症者に対し、Transfer Packageの工夫を行った一例　　　　　　　　　　　　　　　
Sep. 2018

修正版下肢CI療法前後の脳構造(Voxel-based morphometry)の変化
Jun. 2018

電気刺激療法を併用した集中的課題指向型訓練が有効であった脳卒中重度上肢麻痺例　　　　　　　　　　　　　　　
Oct. 2017

経皮的神経電気刺激と課題指向型訓練の併用が慢性期脳卒中片麻痺者の歩行能力に及ぼす影響　　　　　　　　　　　　　　　
Oct. 2017

慢性期脳卒中下肢麻痺1例に対する下肢CI療法の試み
Sep. 2017

慢性期脳卒中例に対する下肢CI療法の治療効果と脳機能結合性の変化　　　　　　　　　　　　　　　
Sep. 2017

重度片麻痺患者に対する装具療法を併用したCI療法の試み　　　　　　　　　　　　　　　
Sep. 2016

回復期重度片麻痺者に対するCI療法と装具療法を併用して実施した一例
Aug. 2016

回復期でのCI療法介入後の上肢運動機能と使用頻度の長期経過と関連性
2014

高次脳機能障害者の単独外出獲得に求められる要素についての検討　　　　　　　　　　　　　　　
2014

当センターにおける車いすレンタルシステムの利点と課題
2013

Apr. 2024 - Present
日本小児理学療法学会　　　　　　　　　　　　　　　

May 2021 - Present
日本神経理学療法学会　　　　　　　　　　　　　　　

Apr. 2012 - Present
日本理学療法士協会