Feb. 2025

Dec. 2024

Oct. 2022

Community health education led by faculty pharmacists and pharmacy students: A pilot study of feasibility and effects on health-seeking attitudes and self-medication literacy.
Hideto Takahashi; Michiko Obara; Masanori Suzuki; Mina Harada; Eiji Fukuda; Kenichi Horie; Takayuki Yoshida
Currents in pharmacy teaching & learning, 08 Sep. 2026
BACKGROUND: Community pharmacist utilisation in Japan remains low despite the Health Support Pharmacy (HSP) framework: approximately 7.6% of residents have a regular pharmacist and only 8.6% are aware of the HSP framework. In this context, connecting residents with pharmacists is worthwhile, and community health education can make pharmacists more visible and approachable. The Health Café program pursues this while also serving as an experiential-learning model, positioning faculty pharmacists as content providers and pharmacy students as dialogue facilitators. OBJECTIVE: To assess the feasibility of the Health Café model and its effects on residents' consultation sources, health-seeking attitudes, and self-medication literacy. METHODS: Feasibility (participation, questionnaire completion, as-planned conduct) was summarized descriptively. Two sessions with independent samples used single-arm pre-post designs (N = 49 and N = 22), analysed at the participant level. The study was approved by the Institutional Review Board of Teikyo Heisei University (No. 2025-080). FINDINGS: Feasibility was demonstrated: enough residents participated (49 and 22), questionnaire completion was near-complete (100% and 95.5%), and it was held as planned without problems. In the first, pharmacist selection rose from 2.0% to 40.8% (p < 0.001). In the second, the largest improvement was in anxiety about health and medicines (p = 0.070); this and the other four - self-care, pharmacist-consultation decisions, trust in the pharmacist, and intention to consult one - were non-significant (all p > 0.05). IMPLICATIONS: The Health Café proved feasible and promising for its three aims - connecting residents with pharmacists, making them visible and approachable, and an experiential-learning model. A larger controlled study with student-outcome measures is warranted.

Food Packaging Materials for One-Dose Packaging for Enhanced Stability of Hygroscopic Medications
Takayuki Yoshida; Kiyotaka Ushijima; Natsumi Nishimura; Makoto Toda; Miho Morikawa; Kazuhiro Iwasa; Takashi Tomita
Pharmaceuticals, 16 Jan. 2026, [Reviewed]
Background/Objectives: One-dose packaging is beneficial for older adults and those on multiple medications because it ensures that no doses are missed and supports medication adherence. However, conventional one-dose packaging materials have high moisture permeability, making them unsuitable for the storage of hygroscopic medications. We evaluated the barrier performance of food packaging materials against moisture and oxygen and investigated their potential to enhance the physical stability of the highly hygroscopic sodium valproate, under stressed storage conditions. Methods: Barrier performance was evaluated by measuring the water vapor transmission (WVTR) and oxygen transmission rates of each packaging material. Then, we evaluated the stability of sodium valproate tablets in different food packaging films by measuring weight change, breaking force, and visual appearance over 14 days under stressed storage conditions (35 °C and 75% relative humidity). Conventional cellophane-laminated polyethylene was used as the reference. Results: The WVTR of the food packaging films were below 2 g/m2/day, less than that of the conventional material. Tablets stored in Materials A and B showed weight increases of no more than 1.2% after 3 days, whereas the maximum increase among all food films was 3.7% (Material C). For Materials A and B, the breaking force remained measurable and the visual appearance unchanged throughout the 14-day period, whereas Material C became unmeasurable by day 14. Tablets packaged in cellophane-laminated polyethylene exhibited deliquescence, with visible deformation and stickiness within 3 days, rendering them unmeasurable. Conclusions: Food packaging materials with high barrier performance offer a practical, safe, and effective solution for one-dose packaging of hygroscopic medications, potentially expanding their clinical use and improving adherence.

Investigation of the Current Status and Challenges of Pharmacists' Community Activities in Japan
Mina Harada; Michiko Obara; Takayuki Yoshida; Miwako Kamei
Pharmacometrics, Dec. 2025, [Reviewed]

Pharmacists' Medication Support for Dysphagia and Involvement in Loneliness and Social Isolation : A Cross-sectional Profile
Shinya Sugiura; Satoshi Yoshid; Keiko Ueda; Takayuki Yoshid; Mina Harad; Mao Murata; Asuka Mitsui; Toru Wakuda; Akihito Ued; Michiko Obara
Pharmacometrics, Dec. 2025, [Reviewed]

Study of Usefulness of Second-Year Pharmacy Students' in-class "Yakuiku" Experience. - To Train Pharmacists Who Can Conduct Health Knowledge Dissemination and Awareness-Raising Activities in the Future -　　　　　　　　　　　　　　　
Mina Harada; Michiko Obara; Takayuki Yoshida; Mami Kikuchi
Pharmacometrics, May 2025, [Reviewed]

Stability assessment of hygroscopic medications in one dose packaging using community pharmacist surveys and experimental storage methods
Takayuki Yoshida; Hisashi Iijima; Yumeka Washio; Makoto Toda; Miho Morikawa; Kazuhiro Iwasa; Takashi Tomita
Scientific Reports, 18 Feb. 2025, [Reviewed]
A survey of community pharmacists identified hygroscopic medications unsuitable for one-dose packaging. Stability testing showed that storage without moisture-suppression bags caused significant changes in weight and breaking force despite minimal visual changes, whereas moisture-suppression bags preserved the quality of some medications, highlighting the need for improved evaluation criteria and pharmacist awareness.

Development of a novel moisture-suppression bag for the preservation of hygroscopic medications.
Taisuke Matsuo; Takayuki Yoshida; Kiyotaka Ushijima; Takashi Doi; Yasuyuki Sadzuka; Takashi Tomita
Journal of pharmaceutical health care and sciences, 15 Feb. 2023, [Reviewed]
We developed a moisture-suppression bag for one-dose packaging of hygroscopic medications without using desiccating agents. The bag maintained internal humidity at 30–40% under high temperature and humidity and suppressed moisture absorption of potassium aspartate and sodium valproate tablets more effectively than conventional plastic bags with desiccants, offering a safer option for elderly patients.

Survey on Heated Tobacco Products in Smoking Prevention Education by School Pharmacists
Takayuki yoshida; Masakazu ishii
japaniese journal of social pharmacy, 10 Dec. 2022, [Reviewed]

Efforts to accurately determine the amount of anti-cancer drugs remaining in the healthcare environment to help improve the working environment
Masanari Takahashi; Takashi Tomita; Hirotake Takeuchi; Shunsuke Kumazawa; Takayuki Yoshida; Kenji Sumiya; Shuji Hishikawa; Masayuki Kojima
Cancer and Chemotherapy, Dec. 2022, [Reviewed]

Visualizing fluid transport inside orally disintegrating tablets and changes in tablets using real-time X-ray radiography and X-ray computed tomography
Kazuhiro Suzuki; Masahiko Yoshiki; Norio Nishikawa; Tsutomu Harada; Yoshiaki Fujita; Yuji Terui; Takayuki Yoshida; Takashi Tomita
Drug Development and Industrial Pharmacy, 12 Aug. 2022, [Reviewed]
Using synchrotron radiation–based X-ray imaging without contrast agents, we investigated the disintegration behavior of wet- and dry-compressed orally disintegrating tablets. Real-time radiography and X-ray computed tomography revealed faster water penetration in wet-compressed tablets, greater swelling in dry-compressed tablets, and void formation after water absorption.

製剤情報に基づいた日本薬局方崩壊試験法と口腔内崩壊錠試験器による崩壊時間の比較 ～ドネペジル口腔内崩壊錠を対象とした検討～
Jul. 2022, [Reviewed]

居住系介護施設における誤薬事故の減少及び至適薬物治療の実現に向けた薬剤師の取り組み
Mar. 2022, [Reviewed]

地域ケアの実践 松戸市常盤平地区事例集 −この教訓を全国に−　　　　　　　　　　　　　　　
Joint work
May 2017

「薬物動態の理解度向上」は「薬物治療の安全」につながることへの期待　　　　　　　　　　　　　　　
Oct. 2025

介護施設の薬剤師配置がスタッフの認識と意識に与える影響　　　　　　　　　　　　　　　
Oct. 2025

居住系介護施設の誤薬事故減少に向けた松戸市薬剤師会の取り組み　　　　　　　　　　　　　　　
Sep. 2024

「薬物動態の理解度向上」から「薬物治療の安全」への期待　　　　　　　　　　　　　　　
Sep. 2024

千葉県内薬局薬剤師を対象とした法的責任の認知度及び賠償責任保険加入状況の実態調査　　　　　　　　　　　　　　　
Sep. 2023

医療環境中に残留する抗がん薬量を正確に把握して労働環境の改善に貢献するための取り組み　　　　　　　　　　　　　　　
Oct. 2022

スマートフォンの録画機能を用いたビデオデブリーフィングによる医療コミュニケーション教育の手法と効果　　　　　　　　　　　　　　　
Mar. 2022

かかりつけ薬剤師は地域でどんな役割を果たせるのか 地域薬剤師会の在宅における麻薬譲渡を含む地域内連係と365日対応に向けての取り組み(「松戸システム」として)　　　　　　　　　　　　　　　
Apr. 2018

薬局と診療所との連携 早期認知症への対応　　　　　　　　　　　　　　　
Feb. 2018

千葉県内保険薬局における調剤事故発生時の対応状況調査報告　　　　　　　　　　　　　　　
Oct. 2017

来局者から地域へ 活動範囲を広げた認知症対応報告　　　　　　　　　　　　　　　
Oct. 2016

PHARM-2E分析法による研修報告とアンケート結果から分かる今後の課題　　　　　　　　　　　　　　　
Nov. 2015

薬局と診療所連携における薬局薬剤師の『気づき』『つなぎ』による認知症疑い早期対応の有用性検討　　　　　　　　　　　　　　　
Nov. 2015

地域薬剤師会の在宅における麻薬譲渡を含む地域内連携と365日対応にむけての取組み　　　　　　　　　　　　　　　
Oct. 2014

2022
日本老年薬学会　　　　　　　　　　　　　　　

Sep. 2021
日本薬局学会　　　　　　　　　　　　　　　

Aug. 2021
日本医療薬学会　　　　　　　　　　　　　　　

Jul. 2021
日本社会薬学会　　　　　　　　　　　　　　　

A Study on the Development of a Machine Learning–Based System to Support the Certification Review Process in Long-Term Care Needs Assessment Committees　　　　　　　　　　　　　　　
Teikyo Heisei University
Apr. 2025 - Mar. 2028